Research

Welcome to the "Scientific Research" subpage on rpq-qpn.org! We are glad that you are interested in our research work. On this page, we provide detailed information about our research, methodology, results and our scientific publications. Our goal is to improve our understanding of the genetic basis of Parkinson's disease and its various motor subtypes.

Our Research

Meta-analysis of the Genome-wide Association Study (GWAS).

Our main research focuses on meta-analysis of data from genome-wide association studies (GWAS). GWAS is a powerful tool that identifies genes associated with various diseases and traits. In our project, we are collecting and analyzing data from numerous GWAS studies on Parkinson's disease.

Research Objectives

- Genetic Marker Identification: Our goal is to identify specific genetic markers associated with different motor subtypes of Parkinson's disease.
- Genetic Characterization of Subtypes: We are studying how different genetic variants affect motor symptoms and disease progression.
- Understanding Molecular Mechanisms: We are working to understand the molecular mechanisms that underlie the genetic variations associated with Parkinson's disease.

Methodological Approach

Our research relies on advanced data analysis techniques that allow us to accurately process and interpret large genetic datasets.

Data Collection

We collect data from a variety of sources, including public and private databases that contain information on the genomes of people with Parkinson's disease. We collaborate with numerous research institutions and medical organizations to access the widest possible range of data.

Genetic Analysis

We use advanced artificial intelligence (AI) and machine learning (ML) algorithms to process and analyze data. These technologies allow us to identify subtle genetic patterns that may be associated with different subtypes of Parkinson's disease.

Validation of Results

The results of our analyses undergo rigorous validation to ensure that they are reliable and have real clinical relevance. We work with experts in various fields to validate our findings and apply them to clinical practice.

Results and Discoveries

Our research has already yielded a number of important findings that contribute to a better understanding of the genetic basis of Parkinson's disease.

- New Genetic Markers: We have identified several new genetic markers that may be associated with different motor subtypes of Parkinson's disease.
- Differences in Gene Expression: We found that different genetic variants can affect gene expression in ways that affect motor symptoms.
- Potential Therapeutic Targets: Our research identifies new potential therapeutic targets that can be used to develop more effective therapies.

Scientific Publications

Our findings have been published in reputable scientific journals, demonstrating the high quality of our research. Here are some of our most important publications:

1. "Genetic Markers and Motor Subtypes in Parkinson's Disease: A Comprehensive GWAS Meta-Analysis"
   - Authors: Dr. Anna Kowalska, Prof. Jan Nowak, Dr. Ewa Lis, Dr. Marek Zieliński
   - Journal: Journal of Neurogenetics.
   - Year of publication: 2023

2. "AI-Driven Identification of Genetic Variants Associated with Parkinsonian Motor Symptoms "
   - Authors: Dr. Ewa Lis, Prof. Jan Nowak
   - Journal: Genomics Today.
   - Publication year: 2022

3. "Molecular Mechanisms Underlying Genetic Differences in Parkinson's Disease Motor Subtypes"
   - Authors: Dr. Anna Kowalska, Dr. Marek Zieliński
   - Journal: Neurobiology Reviews.
   - Publication year: 2021

Research Collaboration

We collaborate with numerous research institutions, hospitals and medical organizations around the world. Our partnerships allow us to access a wide range of data and share knowledge and resources, which is crucial to the success of our research.

How Can You Support Our Research?

Your support is crucial to the continuation and development of our research. Here are some ways you can support us:

- Donations: Every donation helps us fund our research and technology.
- Research Participation: If you are a patient, you can participate in our research and contribute to the advancement of science.
- Scientific Collaboration: If you are a scientist or doctor, we welcome you to collaborate and exchange knowledge.